THREAD seeks to standardize remote patient research.
Our first step is simplicity.


A deliberate, measured approach is key.


Innovation includes risk. However, when working in the field of clinical trials, patient safety, security and data integrity must supersede ambition by a significant margin. Our role at THREAD is to push remote patient research forward at the speed of GxP. 

Our diverse team includes experienced leaders in digital/mobile health. Their combined expertise covers everything from patient engagement to technology development, from project management to quality and security. The THREAD team is supported by our leadership team noted below.



JEFF FRAZIER   Founder & Chief Executive Officer

Jeff founded THREAD in 2005, focused on the design and development of web technologies, mulit-touch displays and eventually apps. His attention later turned to connected health, new ways to conduct clinical research and the promise of remote patient research. You will now find Jeff doing whatever it takes to learn human biological truths faster. At the moment that means bringing clinical research to your pocket. Soon it will mean leveraging AI to drive the entire research loop.

Jeff is a family man and can often be found talking about his wife, six daughters and one son.


SEAN VASSILAROS  Partner & Chief Operating Officer

Sean has spent 14 years in technology and operations. He has focused the last 10 years in healthcare, with a passion for helping people. Sean joined THREAD in October 2011 and has been instrumental in operationalizing and bringing each new THREAD technology to market.

In his free time, Sean enjoys spending time with his family, serving as a volunteer Scoutmaster and acting as Chairman of the Board for The Hailey Mayz Foundation - a charity he started in his daughter's honor that serves special needs children and their families at


JOHN REITES  Partner & Chief Product Officer

Executive intrapreneur turned digital health entrepreneur, John’s career includes over 14 years leading global drug development and healthcare innovation. Named one of the Top 100 Influencers in Digital Health, John provides expertise and execution experience in digital health strategy, remote patient research and care, virtual clinical trials, Phase I - IV clinical research, patient reported outcomes, patient engagement, mobile health, omni-channel experience and virtual reality.

John is a keynote speaker at global industry events, guest lecturer at Duke University on digital health/innovation and a published author featured in various conferences, journals, articles and media outlets.

As Chief Product Officer, Partner at THREAD, John leads THREAD’s digital health platform enabling remote patient research conducted by biopharmaceutical companies, CROs and academic researchers.




THREAD CPO John Reites quotes in recent Healthcare IT News article Read Here

THREAD and Medidata have partnered together to provide clients with an end-to-end platform Learn More

ProofPilot launches digital health study templates for clinical research Learn More

ResearchKit update: Notes from the field on trial retention, Android integration, and more Learn More

John Reites Joins THREAD Research as Chief Product Officer and Partner Learn More

The Apple Watch could soon predict seizures, thanks to Johns Hopkins University Learn More


May 24, 2017: THREAD CPO John Reites included in report on Digital Health innovation in the Triangle, NC.

May 23, 2017: THREAD CPO John Reites to co-host at Medidata mHealth Boston Dinner

May 23, 2017: THREAD CEO Jeff Frazier to judge the $500k Mood Challenge Learn More

May 3, 2017: Jeff Frazier to participate in panel on Remote Patient Research in San Diego Learn More

April 19, 2017: Discover how Medidata & THREAD Research are bringing a tailored app experience to clinical trials Learn More

April 6, 2017: THREAD CEO Jeff Frazier lead panel discussion at Clinical Trials Patient Experience Summit Learn More

March 14, 2017: SXSW On Demand: Interactive Virtual Health Research Panel Learn More

February 1, 2017: Digital Health Today Podcast on the Virtualization of Clinical Research featuring THREAD's John Reites: Listen Now

December 20, 2016: Intrepreneur to Entrepreneur – John Reites Listen Now