Objective 1
Capture perceptions of the overall clinical trial experience
Use CaseEvaluation of Clinical Trial Recruitment Assets
Leveraging the Patient Voice to Collect Lupus Patient Input on Clinical Trial Recruitment Materials
In preparation to recruit for a clinical trial, the pharmaceutical sponsor sought to better understand perceptions, impact and clarity of proposed participant-facing recruitment materials
Industry:Pharmaceutical
Type:Clinical Trial Recruitment Optimization
Timeline:48 hours
TrialPulseClinical Trial RecruitmentLupusPatient ExperienceMaterials ValidationVoice ResearchRecruitment Optimization
Objective 2
Measure perceived impact of the trial
Objective 3
Determine perspectives on understanding and clarity of materials
The inVibe Solution
The inVibe Solution
inVibe’s TrialPulse solution captured lupus patient feedback on recruitment materials so the sponsor could refine clarity, completeness, and appeal before launch.
- Voice-powered research methodology
- 48-hour rapid recruitment capability
- Automated phone interview system
- Advanced NLP tools and speech-emotion recognition
- Interactive online dashboard
- Multi-dimensional analysis (content, language patterns, emotional assessment)
- Diverse patient community representation
How We Did It
1
Collect
Collect
Within 48 hours, inVibe recruited 20 lupus patients spanning a diverse community. After reviewing the study materials online, participants joined automated phone interviews to share their impressions.
Participants
Total: 20 Lupus patients representing a diverse cross-section of the community
Recruitment Time: 48 hours
Method: Automated phone interviews via computer or smartphone
Key Questions
Q1
How easy or difficult is the “Study Description” section to understand? What specific words or phrases do you find potentially confusing or unclear? And how might they be improved?
Q2
Please refer to the section titled “Arms and Interventions,” which describes the medications being studied in the trial, and who receives each medication. In your own words, how would you explain this clinical trial to a friend or family member?
Q3
Please refer to the section titled “Outcome Measures” which explains how the investigators will decide if the experimental treatment is working. What are your overall reactions to these treatment goals? What, if anything, would you add to this list?
Q4
Imagine that you were looking to enroll in a clinical trial for lupus and this was one of many trials you came across. How likely would you be to consider enrolling in this trial, and for what reasons specifically?
2
Analyze
inVibe’s analysts used language expertise and advanced NLP to evaluate what patients said, how they said it, and how it sounded, highlighting where the materials resonated and where they didn’t.
Techniques
- Language expertise and advanced NLP tools
- Speech-emotion recognition
Focus Areas
- What is Said: Summarize and categorize the content and themes
- How it’s Said: Identify the language patterns and construction
- How it Sounds: Utilize machine learning and acoustic technology to assess the emotionality
3
Deliver
Deliver
The client was provided with an interactive report via an online dashboard, along with the voice data, transcripts, and a high-level analysis. An in-house analyst walked the client through all of the most meaningful data, supporting each insight with specific voice data.
- Interactive online dashboard housing voice data, transcripts, and analysis
- In-house analyst walkthrough supporting insights with patient voice moments
- Audiogram tools to create kinetic text videos
- Listening Labs interactive stories assembled from transcripts, audio, and charts
- Expert Perspective sessions led by inVibe analysts
Reworked recruitment materials with clearer language, a plan for side effects, and a visual timeline.
The refreshed assets help patients grasp expectations quickly and feel more confident about considering enrollment.
Insights & Next Steps
Key Insights & Recommendations
Based on the insights, inVibe recommended that the team take the following actions to optimize their patient-facing materials.
Completeness of Content
Patients worried about the lack of information provided regarding potential side effects. These missing details led them to make assumptions, which caused additional worry. inVibe recommended providing more details on potential side effects and a plan to manage them should they encounter these.
Ease of Participation
Patients felt the overall trial participation requirements were reasonable and would not be a significant barrier. Only a few respondents deemed the 48-week timeframe “too long” and questioned their ability to commit. inVibe recommended including a visual timeline that depicts the time commitment requirements.
Clarity of Language
Patients expressed confusion over the terminology and potential outcomes. Those who struggled to understand the materials were more likely to say they would NOT consider participating in this trial. inVibe recommended supplying a glossary of terms and further clarifying the study endpoints.
